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1P-LSD also known as 1-propionyl-LSD and 1-propionyl-lysergic acid diethylamide, is the 1-propionyl analog of LSD.
IUPAC: 1-propionyl-lysergic acid diethylamide
Molecular Mass: 379.45926g/mol
Molecular Formula: C23H29N3O2
1p-LSD, short for 1 Propionyl Lysergic Acid Diethylamide is the hallucinogenic, psychedelic drug that belongs to the family of lysergamide.
Surprisingly it is structurally similar to LSD and ALD 52 which suggests it has an identical effect profile as well. With the lack of research related to this substance, every argument related to the pharmacology of this drug is completely according to its structure and the subjective effect that are not different from other such lysergamides.
According to its molecular structure
It acts as the partial agonist of 5 HT2A. Psychedelic effects come from efficacy at 5HT2A receptors. The role of such interactions and how these result in psychedelic experience always remain elusive.
Moreover, it has been theorized that 1p-LSD is a prodrug to LS. It shows only 35% potency of LDS in mice. The LSD is detected with the help of LC-MS when the 1p-LSD is incubated in Human Serum. This means that 1p-LSD doesn’t only act as a prodrug for LSD but also, it directly acts as a serotonin receptor against its very own rights.
1P-LSD Subjective Effects
Physical Effects
Tactile Sensations
Stimulation
Bodily controlled enhancement
Nausea
Tactile improved
Pupil Dilation
Increase heart rate
Cognitive Effects
Current mind state enhancement
Thought acceleration
Novelty enhancement
Immersion enhancement
Time distortion
Ego death
Mindfulness
Auditory Effects
Distortions
Hallucination
Enhancement
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